Shire's soon-to-depart Chief Financial Officer, Graham Hetherington, sold 2.29m pounds-worth of shares in the pharmaceutical giant. Hetherington, who on Friday annonced his intention to step down at the beginning of March to spend more time with his family, exercised a stock appreciation right award of 134,814 shares, of which he subsequently received and sold 72,821. The share were exercised at 1,443p each, and sold at 3,146.7p. His interim replacement will be Senior Vice President and Group Financial Controller, James Bowling. Top Director BuysVedanta Resources (VED) Director name: Mr Anil AgarwalAmount purchased: 18,404 @ 892.00p Value: £164,164Avesco Group (AVS) Director name: Mr Richard A Murray-ObodynskiAmount purchased: 100,000 @ 108.37p Value: £108,370Maven Income & Growth VCT (MIG1) Director name: Mr John D W PocockAmount purchased: 14,999 @ 67.67p Value: £10,150Top Director SellsShire Plc (SHP) Director name: Mr Graham HetheringtonAmount sold: 72,821 @ 3,146.75p Value: £2,291,495Helical Bar (HLCL) Director name: Mr Jack PitmanAmount sold: 275,000 @ 376.54p Value: £1,035,485Helical Bar (HLCL) Director name: Mr Gerald A KayeAmount sold: 250,000 @ 376.54p Value: £941,350Helical Bar (HLCL) Director name: Mr Michael SladeAmount sold: 150,000 @ 376.54p Value: £564,810Beazley (BEZ) Director name: Mr Andrew HortonAmount sold: 207,460 @ 263.60p Value: £546,865Beazley (BEZ) Director name: Mr Clive WashbournAmount sold: 188,394 @ 263.60p Value: £496,607Beazley (BEZ) Director name: Mr Clive WashbournAmount sold: 172,946 @ 263.60p Value: £455,886Beazley (BEZ) Director name: Mr Martin BrideAmount sold: 144,122 @ 263.60p Value: £379,906Beazley (BEZ) Director name: Mr Andrew HortonAmount sold: 138,394 @ 263.60p Value: £364,807Beazley (BEZ) Director name: Mr Adrian Cox Amount sold: 131,876 @ 263.60p Value: £347,625NR