With profits down nearly half at the pub group Mitchells and Butlers, shares in the All Bar One owner are 10% lower. The firm also parted company with chief executive Tim Clarke today. Enterprise Inns, also a pub group but one that rents premises to tenants, is also lower. South African private bank Investec, which saw full year profit tumble 22% following a sharp decline at its investment banking and private banking businesses, is also lower.Among the risers is defence group QinetiQ, which posted a sharp rise in revenues and underlying pre-tax profits.FTSE 250 - RisersStagecoach Group (SGC) 132.75p +3.11%Sports Direct International (SPD) 72.00p +2.86%Vectura Group (VEC) 70.00p +2.19%Robert Wiseman (RWD) 383.00p +2.13%QinetiQ Group (QQ.) 146.50p +1.91%Brown (N.) Group (BWNG) 244.50p +1.87%SSL International (SSL) 519.00p +1.76%Heritage Oil (HOIL) 518.00p +1.57%Rank Group (RNK) 64.75p +1.17%Morgan Sindall (MGNS) 647.50p +0.94%FTSE 250 - FallersMitchells & Butlers (MAB) 236.50p -9.47%Enterprise Inns (ETI) 146.00p -8.03%Salamander Energy (SMDR) 178.00p -7.05%COLT Telecom Group S.A. (COLT) 116.00p -7.01%Euromoney Institutional Investor (ERM) 212.50p -6.90%SEGRO (SGRO) 25.00p -6.54%Inchcape (INCH) 18.75p -6.25%Moneysupermarket.com (MONY) 54.50p -6.03%HMV Group (HMV) 121.25p -5.83%Investec (INVP) 312.75p -5.66%