C&W Worldwide is doing its best the pull the index lower, falling over 15% after it issued its second profit warning within a year. The telecoms titan now expects flat earnings next year compared with earlier market forecasts of an increase of over £20m from £444m to £470m.The best performing stock is plastic packaging firm RPC, after revealed that revenues for the 2010/11 financial year will be well ahead of last year.The transport sector is heading higher on the FTSE 250 as rail and bus operators rushed statements celebrating being on the shortlists for the east and west coast UK rail franchises. Stagecoach, FirstGroup, Go-Ahead and National Express are all firmer.Oil firm Premier Oil notched up record revenue and profit in 2010 as oil and gas prices rocketed higher, sending shares higher.Budget airline easyJet is firmer after an upgrade from broker Charles Stanley. The broker raised its rating from 'reduce' to 'hold' following the recent share price weakness.FTSE 250 - RisersRPC Group (RPC) 271.10p +11.93%Kofax (KFX) 510.00p +6.69%Barratt Developments (BDEV) 116.10p +6.32%Punch Taverns (PUB) 74.05p +5.94%SIG (SHI) 138.90p +5.87%Debenhams (DEB) 63.70p +5.64%Hochschild Mining (HOC) 655.00p +5.05%Grainger (GRI) 108.20p +4.44%Ocado Group (OCDO) 215.00p +4.12%Afren (AFR) 160.10p +3.96%FTSE 250 - FallersCable & Wireless Worldwide (CW.) 53.70p -15.17%Drax Group (DRX) 372.80p -4.95%Domino's Pizza UK & IRL (DOM) 440.50p -3.08%Rank Group (RNK) 146.80p -2.33%Imagination Technologies Group (IMG) 428.70p -2.26%Savills (SVS) 356.40p -1.87%EnQuest (ENQ) 135.20p -1.74%Laird (LRD) 138.90p -1.63%IG Group Holdings (IGG) 467.80p -1.41%Shanks Group (SKS) 113.40p -1.39%