Director dealings: AstraZeneca CFO ups stake

8th May 2019 16:18

(Sharecast News) - AstraZeneca chief financial officer Marc Dunoyer purchased 8,500 ordinary shares in the FTSE 100-listed pharmaceuticals outfit on Tuesday.Dunoyer, who took over as CFO back in October 2013, acquired the shares at an average price of 5,800p each, for a total value of £493,000, the company said in a statement.AstraZeneca and its partner Daiichi Sankyo Company announced positive top-line results for the pivotal phase 2 'DESTINY-Breast01' trial of trastuzumab deruxtecan (DS-8201) on the following day.The group said the HER2-targeting antibody drug conjugate (ADC) and potential new medicine was evaluated in patients with HER2-positive, unresectable and/or metastatic breast cancer previously treated with trastuzumab emtansine.It said the response rate in DESTINY-Breast01, as assessed by an independent review committee, confirmed in a "heavily-pretreated, global" patient population the "unprecedented" clinical activity in the recently-published phase 1 trial.The safety and tolerability profile of trastuzumab deruxtecan was also consistent with previous experience.As of 1620 BST, AstraZeneca shares were up 0.88% to 5,851p.Top Director BuysAstraZeneca (AZN)Director name: Mr Marc DunoyerAmount purchased: 8,500 @ 5,800.00pValue: £493,000 VPC Specialty Lending Investments (VSL)Director name: Mr Richard LevyAmount purchased: 73,383 @ 72.00pValue: £52,836 Mereo Biopharma Group (MPH)Director name: Mr Anders EkblomAmount purchased: 46,700 @ 109.20pValue: £50,996 Drax Group (DRX)Director name: Mr Andy SkeltonAmount purchased: 15,000 @ 331.32pValue: £49,698 International Personal Finance (IPF)Director name: Mr Bronwyn SyiekAmount purchased: 20,000 @ 176.25pValue: £35,250 Domino's Pizza Group (DOM)Director name: Mr David BauernfeindAmount purchased: 12,000 @ 260.38pValue: £31,246 International Personal Finance (IPF)Director name: Mr John MangelaarsAmount purchased: 15,000 @ 174.35pValue: £26,152 NMC Health (NMC)Director name: Mr Mark TompkinsAmount purchased: 642 @ 2,849.23pValue: £18,292 EnQuest (ENQ)Director name: Mr Helmut LangangerAmount purchased: 87,302 @ 20.00pValue: £17,460 Top Director SellsSerco Group (SRP)Director name: Mr Rupert SoamesAmount sold: 544,541 @ 124.97pValue: £680,513 Serco Group (SRP)Director name: Mr Angus CockburnAmount sold: 283,516 @ 124.97pValue: £354,310 Serco Group (SRP)Director name: Mr David EveleighAmount sold: 18,629 @ 124.97pValue: £23,281 NMC Health (NMC)Director name: Mr Mark TompkinsAmount sold: 642 @ 2,846.24pValue: £18,273