AstraZeneca's Chief Executive Officer, Pascal Soriot, has spent £2m on shares, the drugs giant announced on Tuesday. The director, who has held his role since October 2012, paid 4,345p for each of the 46,200 shares. It follows another large purchase made by a member of the Astra board last week, when Chief Financial Officer Marc Dunoyer purchased 20,000 shares at 4,340p each in a deal worth £868,000. That came the same day the group announced that an advisory committee to the US Food and Drug Administration (FDA) voted 11 to two that there was not enough evidence to support an accelerated approval for the use of olaparib as a maintenance treatment for women with a specific type of ovarian cancer. Top Director BuysAstraZeneca (AZN) Director name: Mr Pascal SoriotAmount purchased: 46,200 @ 4,345.00p Value: £2,007,390Liontrust Asset Management (LIO) Director name: Mr John Stephen IonsAmount purchased: 106,657 @ 253.00p Value: £269,842Liontrust Asset Management (LIO) Director name: Mr Vinay Kumar AbrolAmount purchased: 71,104 @ 253.00p Value: £179,893Sanditon Investment Trust (SIT) Director name: Mr Christopher A KeljikAmount purchased: 150,000 @ 100.00p Value: £150,000Sanditon Investment Trust (SIT) Director name: Mr Hugo DixonAmount purchased: 140,000 @ 100.00p Value: £140,000Chemring Group (CHG) Director name: Mr Peter HicksonAmount purchased: 50,000 @ 205.00p Value: £102,500Sanditon Investment Trust (SIT) Director name: Mr Charles HarmanAmount purchased: 100,000 @ 100.00p Value: £100,000Acal (ACL) Director name: Mr Richard J MoonAmount purchased: 14,000 @ 385.88p Value: £54,023Sanditon Investment Trust (SIT) Director name: Mr Rupert BarclayAmount purchased: 50,000 @ 100.00p Value: £50,000Liontrust Asset Management (LIO) Director name: Mr Jonathan Hughes-MorganAmount purchased: 15,457 @ 253.00p Value: £39,106Top Director SellsAfren (AFR) Director name: Mr Shahid UllahAmount sold: 600,000 @ 141.00p Value: £846,000Severn Trent (SVT) Director name: Mr Michael J E McKeonAmount sold: 4,358 @ 1,921.00p Value: £83,717Severn Trent (SVT) Director name: Mr Andy SmithAmount sold: 2,655 @ 1,921.00p Value: £51,003Severn Trent (SVT) Director name: Mr Martin KaneAmount sold: 2,358 @ 1,921.00p Value: £45,297Severn Trent (SVT) Director name: Mr Tony BallanceAmount sold: 2,067 @ 1,921.00p Value: £39,707XP Power Ltd. (DI) (XPP) Director name: Mr David Hempleman AdamsAmount sold: 693 @ 1,645.00p Value: £11,400NR