Healthcare firm BTG was on the up after successfully completing the first phase of the US-based trial of Varisolve, a varicose vein treatment. Casinos group Rank was also higher after confirming speculation that it is in talks with Gala Coral about the potential acquisition of Gala's casino business.Meanwhile, miners were tracking metals prices lower, with Allied Gold and Talvivaara both seeing significant losses from the day's trading.Although not in the bottom 10, Egypt-focused gold miner Centamin was a notable faller, despite achieving a record quarter of gold production in the last three months of the financial year, helped by higher output at its flagship Sukari mine and lower operating costs.Insurance underwriter Lancashire Holdings was also lower as it said that it has increased its estimated losses resulting from the floods in Thailand and the Tohoku earthquake in Japan.FTSE 250 - RisersDixons Retail (DXNS) 15.83p +5.53%Supergroup (SGP) 658.00p +4.20%BTG (BGC) 332.00p +2.56%Rank Group (RNK) 129.90p +2.28%Galliford Try (GFRD) 480.70p +2.28%Bumi (BUMI) 863.00p +1.83%BH Global Ltd. GBP Shares (BHGG) 1,154.00p +1.67%Diploma (DPLM) 397.60p +1.56%KCOM Group (KCOM) 70.75p +1.51%Halfords Group (HFD) 322.70p +1.48%FTSE 250 - FallersAquarius Platinum Ltd. (AQP) 182.60p -4.90%Allied Gold Mining (ALD) 138.60p -4.41%International Personal Finance (IPF) 190.00p -4.04%Lonmin (LMI) 1,048.00p -4.03%Cape (CIU) 368.70p -3.98%Afren (AFR) 119.60p -3.55%Howden Joinery Group (HWDN) 106.60p -3.53%Michael Page International (MPI) 380.50p -3.50%Talvivaara Mining Company (TALV) 317.80p -3.17%Kesa Electricals (KESA) 68.85p -3.10%NR