(ShareCast News) - The FTSE 250 was up 287.23 points or 1.74% to 16,801.76, rising sharply on Friday morning on the back of Janet Yellen's comments overnight.Synergy Health shares skyrocketed on the news that a federal court in Ohio has ruled against the Federal Trade Commission's request for a preliminary injunction to block Steris' $1.9bn acquisition of the group.In May, the Federal Trade Commission filed a lawsuit to stop the deal, saying it would both companies' customers by reducing competition between them based on innovative sterilisation techniques.Premier Oil investors were buoyed by news from Falkland Oil and Gas that, along with Rockhopper Exploration, the three parties had agreed to drill a further well on the Isobel/Elaine complex.And it was a general positive trend in the fashion industry with Jimmy Choo, Debenhams and Ted Baker all up.Aggreko took the biggest hit in the FTSE 250, after HSBC downgraded it to a reduce rating.And a downturn the metals market forced share prices down for Acacia Mining and Kaz Minerals.FTSE 250 - RisersSynergy Health (SYR) 2,237.00p +41.58%Evraz (EVR) 74.10p +7.39%Jimmy Choo (CHOO) 149.90p +6.46%Premier Oil (PMO) 67.00p +4.85%Indivior (INDV) 229.20p +4.71%Debenhams (DEB) 79.20p +4.69%Ted Baker (TED) 3,163.00p +4.67%Card Factory (CARD) 398.80p +4.48%Man Group (EMG) 160.30p +4.36%Pennon Group (PNN) 747.50p +3.82% FTSE 250 - FallersAggreko (AGK) 903.50p -3.01%Acacia Mining (ACA) 243.60p -2.99%Kaz Minerals (KAZ) 101.70p -2.96%Mitchells & Butlers (MAB) 322.10p -2.48%Centamin (DI) (CEY) 62.75p -1.57%Nostrum Oil & Gas (NOG) 480.60p -1.50%Polymetal International (POLY) 547.00p -1.35%UDG Healthcare Public Limited Company (UDG) 510.50p -1.16%Sophos Group (SOPH) 240.20p -0.83%Greencore Group (GNC) 288.70p -0.79%